Current guidelines for treating systemic lupus erythematosus (SLE) support weight-based dosing for hydroxychloroquine (HCQ), but the guidelines lack specific recommendations on adjusting the dose based on kidney function or other clinical factors that can... See more
Physical therapy is effective as a first-line strategy for chronic low back pain (LBP), as current practice guidelines state, but the size of the effects is small, according to results of the OPTIMIZE study, which compared outcomes with physical therapy (... See more
Popular niacin (vitamin B3) derivatives, which are readily available in retail stores and often promoted as anti-aging supplements, may have a protective effect on cancer cells, according to a new study. The research, published in Cancer Letters, showed t... See more
Early methadone dose titration (a boost between treatment days 4 and 6) is associated with better treatment retention and reduced risk for opioid toxicity among patients using fentanyl over 6 months of follow-up, according to new data. In response to poor... See more
Use of preexposure prophylaxis (PrEP) for HIV prevention in adolescents and young adults is “strikingly low,” though youth aged 13-24 years have nearly 1 in 5 new HIV infections in the US, according to a new study in JAMA Pediatrics. Use is particularly l... See more
